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dc.contributor.authorPeamaroon, Nipaten_US
dc.contributor.authorนิภัทร เปี่ยมอรุณen_US
dc.contributor.authorMoonrungsee, Nuntapornen_US
dc.contributor.authorนันทพร มูลรังษีen_US
dc.contributor.authorBoonmee, Apapornen_US
dc.contributor.authorอาภาพร บุญมีen_US
dc.contributor.authorSuwancharoen, Sunisaen_US
dc.contributor.authorสุนิษา สุวรรณเจริญen_US
dc.contributor.authorKasemsuk, Teerapichen_US
dc.contributor.authorธีรพิชญ์ เกษมสุขen_US
dc.contributor.authorJakmunee, Jaroonen_US
dc.contributor.authorจรูญ จักร์มุณีen_US
dc.date.accessioned2020-09-07T08:13:27Z
dc.date.available2020-09-07T08:13:27Z
dc.date.issued2020-09-07
dc.identifier.issn2651-1096
dc.identifier.urihttp://repository.rmutp.ac.th/handle/123456789/3354
dc.descriptionวารสารวิชาการและวิจัย มทร.พระนคร, 13(2) : 106-118en_US
dc.description.abstractThe Thai wisdom knows the benefits of Carissa carandas L. to be used as a traditional herbal medicine. However, there was no scientific evidence to show that Carissa carandas L. of Thailand can treat gout or not. In this research, the Carissa carandas L. fruit extract in semi-ripening and ripe stage were studied for the phytochemical and inhibitory activity of xanthine oxidase, one of the causes of gout. The result of hytochemical indicated that the crude extract from semi-ripening stage fruit contained many substances; phenolic compounds, alkaloids, flavonoids, terpenoids, saponins and deoxy sugars. While the ripe stage fruit contained the similar substances excepted saponins. The extract solution of Carissa carandas L. showed the xanthine oxidase inhibitory activity, as the ethanolic extract solution gave the higher activity than water extract solution. The crude extracts of semi-ripening stage fruit presented the higher activity than the ripe stage one with the IC 50 values of 2.40 ± 0.05 and 2.87 ± 0.37 mg/mL, respectively. The result of ripening stage with different phytochemical may be related to inhibition of xanthine oxidase activity. Therefore, the selecting of sampling period and purification of extract may be a choice for using as medicine for gouten_US
dc.description.sponsorshipRajamangala University of Technology Phra Nakhonen_US
dc.language.isothen_US
dc.subjectXanthine Oxidaseen_US
dc.subjectแซนทีนออกซิเดสen_US
dc.subjectCarissa carandasen_US
dc.subjectมะม่วงหาวมะนาวโห่en_US
dc.subjectUric Aciden_US
dc.subjectกรดยูริกen_US
dc.subjectGouen_US
dc.subjectโรคเกาต์en_US
dc.titlePhytochemical and xanthine oxidase inhibitory activity of carissa carandas l. fruit extracten_US
dc.title.alternativeพฤกษเคมีและกิจกรรมยับยั้งเอนไซม์แซนทีนออกซิเดสของสารสกัดจากผลมะม่วงหาวมะนาวโห่en_US
dc.typeJournal Articlesen_US
dc.contributor.emailauthornipat.p@rbru.ac.then_US
dc.contributor.emailauthorarit@rmutp.ac.then_US


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